A few labs I've worked in, from writing pipelines to bench chemistry.
Visiting Student Researcher
Working on a non-invasive way to characterize Richter's transformation, the
often-fatal point where chronic lymphocytic leukemia turns into an aggressive
lymphoma. Cell types shed DNA and RNA into the blood differently, so measuring
cell-free DNA against cell-free RNA can separate the transformed clone from the
leukemia it came from.
Smith Lab · UCSF Department of Medicine
since 2025 Visiting Student Researcher
Rebuilding a high-throughput single-cell DNA and antibody sequencing
pipeline (DAb-seq v2) for leukemia research, so a patient's samples can be
followed across diagnosis, remission, and relapse to study treatment response
and resistance. I wrote a modular C++/Python toolchain that runs on Slurm-based
HPC, about 10× faster than the old one.
Bogyo Lab · Stanford University School of Medicine
2022-24 Visiting Student Researcher
Made and tested peptide-based enzyme inhibitors for drug discovery, aiming
at therapeutics for Staphylococcus aureus. I built the compounds end to end
(Fmoc solid-phase synthesis from phage and mRNA-display hits, purification, NMR
confirmation, enzymatic assays) and co-authored a peer-reviewed paper on
antimalarial proteasome inhibitors.
J. M. Bennett, K. E. Ward, R. K. Muir, S. Kabeche, E. Yoo, T. Yeo, G. Lam, H. Zhang,
J. Almaliti,
G. Berger, F. F. Faucher, G. Lin, W. H. Gerwick,
E. Yeh, D. A. Fidock, M. Bogyo. “Covalent Macrocyclic Proteasome Inhibitors Mitigate
Resistance in
Plasmodium falciparum.”
ACS Infectious Diseases, 2023.